Disease: Ichthyosis, X-Linked
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TNFSF10 P50591 TNF superfamily member 10 Signaling 0.13 0.413 0.885
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TIMM8A O60220 translocase of inner mitochondrial membrane 8A 0.65 0.510 0.846
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TBC1D9 Q6ZT07 TBC1 domain family member 9 Enzyme 2.8E-05 0.399 0.846
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
MUC1 P15941 mucin 1, cell surface associated 1.9E-02 0.384 0.885
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
MLRL Myeloid leukemia-related gene (myeloid tumor suppressor) 0.564 0.769
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
LGALS1 P09382 galectin 1 Signaling 4.5E-03 0.435 0.846
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
HSPB1 P04792 heat shock protein family B (small) member 1 2.8E-07 0.436 0.808
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
HPSE Q9Y251 heparanase Enzyme 2.3E-14 0.425 0.808